AH-DB (Apo and Holo structures DataBase) collects apo and holo structure pairs of proteins. Various protein functions have ben shown directly associated with conformational transitions triggered by binding other molecules. Tertiary structures determined in the unbound and bound state are usually named apo and holo structures, respectively.
AH-DB is the largest database of apo-holo strcture pairs and provide a sophisticated interface to search and view the collected data. It contains 746314 apo-holo pairs of 3638 proteins from 702 organisms. See more detailed statistics.
This video contains a brief introduction about AH-DB and why we have created AH-DB, which stands for Apo-Holo Database.
This video shows how to use AH-DB and generally what everything listed on the site means.